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research chemical stimulants,
intermediate state chemistry
Formular C16H22Cl2N2O Research Chemicals Legal Strong U48800 maf for medical research
1. Quick details
|Pro Name||U48800 maf|
|Delivery Time||Within 2 days after receive payment|
|PackAge||Aluminum foil bag|
|Production Capacity||500 Kilogram/Month|
|Storage||store in dry and cool place.|
|Application||For lab research|
U-48800 is an opioid analgesic drug developed by a team at Upjohn in the 1970s that acts as a selective agonist of the µ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor and has around 7.5 x the potency of morphine in animal models.
U-48800 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold.
Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds, each optimizing one moiety] until they discovered that U-48800 was the most active.
U-48800 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures. Although not used medically, the selective kappa ligands are used in research.
The way in which opioids structurally mimic these natural endorphins results in their euphoria, pain relief and anxiolytic effects. This is because endorphins are responsible for reducing pain, causing sleepiness, and feelings of pleasure. They can be released in response to pain, strenuous exercise, orgasm, or general excitement.
U-47700 may also be an agonist for the kappa-opioid receptor system. As a result of this, it has become the lead compound of selective kappa-opioid receptor ligands such as U-50488 and U-69,593, which share very similar structures. Its structure led to other chemists experimenting with it to see if rigid analogues would retain activity. Although not used medically, the selective kappa ligands are used in research.
4. Company Introduction
Fanchuang Medical Biotechnology Co., Ltd. specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on.
Products: Cannabinoids(5f-adb, bb-22, sdb-005......); Stimulants(a-pvp, M1, Methylone, he-xen, pvp......);
Hot sell products: 4CEC；4cdc; maf 2fdck; npvp thpvp and so on
Our products are produced on the basis of best technical team, advanced equipment, high qualified management which meets the requirements of security and environmental protection.
We earned customers' trust and created a good reputation during these years. we are committed to providing excellent quality products and the perfect service to friends all over the world.
We will provide the most comprehensive products and service to you!
We are looking forward to your cooperation.
1. How is the quality?
The qualities of most products are above 99% purity, same are 99.7% purity.
2. How is the package?
Aluminum foil bag or as customer's required.
3. How is the storage?
Keep in dry and cool place.
4. Do I need to pay extra for shipping cost?
No, our price includes the shipping cost already; you need not pay for any tax and others.
5. Can I order sample to test?
Yes, you are welcome to order sample before placing bulk order. We will send the sample directly to your door by courier.
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