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Bk Methylone Ethylone Molly Research Chemicals BK MDMA 99% Purity CAS 195875-84-4
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dibu adbf mdmc 3-ho-pcp 3-meo-pce 3-meo-pce 3-meo-pcmo 4-meo-pcp
ru-28306 ro5-4864 5f-adb
Brasofensine (NS-2214, BMS-204756) is a phenyltropane that had been under development for the treatment ofParkinson's and Alzheimer's disease. Phase II trials were conducted in 1996 and brasofensine was shown to be both effective and well tolerated at a dose of 4 mg, however development was stopped after in vivo cis-anti isomerization of the 2α-methyloxime group was reported. In animal models of Parkinson's disease, brasofensine was effective in stimulating LMA and reversing akinesia.
The isomerization of brasofensine is not between the alpha and beta positions on the 2 position of the tropane ring but rather the E/Z isomerization of the imine (i.e. "methyl-aldoxime"). It was believed that this process occurs in vivo although it cannot be ruled out as a possibility that some isomerization also occurs prior to ingestion.
The (Z)-isomer has been consigned the name BMS-205912
In PD, symptoms do not begin to manifest until there has been an 80% reduction in dopaminergic neurons, particularly in the substantia nigra brain region.
Diclofensine (Ro 8-4650) was developed by Hoffmann-La Roche in the 1970s in the search for a new antidepressant. It was found that the (S)-isomer was responsible for activity. Is a stimulant drug which acts as atriple monoamine reuptake inhibitor, primarily inhibiting the reuptake of dopamine and norepinephrine,with affinities (Ki) of 16.8 nM, 15.7 nM, and 51 nM for DAT, NET, and SERT (dopamine, norepinephrine and serotonin transporters), respectively. It was found to be an effective antidepressant in human trials, with relatively few side effects, but was ultimately dropped from clinical development, possibly due to concerns about its abuse potential.
Diclofensine is chemically a tetrahydroisoquinoline (THIQ) derivative, as is nomifensine.
NM-2201 (also known as CBL-2201) is an indole-based synthetic cannabinoid that presumably has similar properties to the closely related 5F-PB-22 and NNE1, which are both full agonists andunselectively bind to CB1 and CB2 receptors with low nanomolar affinity.
Methadone, sold under the brand name Dolophine, among others, is an opioid used to treat pain and as maintenance therapy or to help with tapering in people with opioid dependence. Detoxification using methadone can either be done relatively rapidly in less than a month or gradually over as long as six months. While a single dose has a rapid effect, maximum effect can take five days of use. The effects last about six hours after a single dose and a day and a half after long-term use in people with normal liver function. Methadone is usually taken by mouth and rarely byinjection into a muscleor vein.
Isopropylphenidate (also known as IPH and IPPD) is a based drug, closely related to but with the methyl replaced by an ester. It has similar effects to methylphenidate but with a longer duration of action,[ and was banned in the UK as a T from April 2015 following its unapproved sale as a
It is illegal in Lithuania to use, buy, possess, transport, sell or import Isopropylphenidate
25I-NBOMe (2C-I-NBOMe, Cimbi-5, also shortened to "25I", and colloquially referred to as "N-bomb" is a and derivative of the psychedelicIt was discovered in 2003 by chemist Ralf Heim at the who published his findings in his PhD dissertation. The compound was subsequently investigated by a team at led by
Nimetazepam (marketed under brand name Erimin and Lavol) is an intermediate-acting drug which is a derivative. It was first synthesized by a team at Hoffmann-La Roche in 1962. It possesses andproperties. Nimetazepam is also an It is sold in 5 mg tablets known as Erimin and Lavol. It is generally prescribed for the short-term treatment of in patients who have difficulty falling asleep or maintaining sleep. The sole global manufacturer of Nimetazepam (Sumitomo Japan) has ceased manufacturing Erimin since early November 2015. Patients being prescribed Erimin are being switched to other hypnotics, e.g. etc.
2C-B or 2,5-dimethoxy-4-bromo is a of the. It was first synthesized by in 1974. In Shulgin's book , the dosage range is listed as 12–24 mg. 2C-B is sold as a white powder sometimes pressed in tablets or gel caps and is also referred to by a number of other names.The drug is usually taken orally, but can also be or vaporized.
6-MAPB (1-(benzofuran-6-yl)-N-methylpropan-2-amine) is a psychedelic and entactogenic drug which is structurally related to 6-APB and MDMA. It is not known
5-MAPB (1-(benzofuran-5-yl)-N-methylpropan-2-amine) is an similar to on its structure and effects.
Oxycodone has been in clinical use since 1916, and it is used for managing moderate to moderately severe acute or chronic It has been found to improve for those with many types of pain.[ Experts are divided regarding use for non cancer-related chronic pain, as most opioids have great potential for dependence and may also create
Diclazepam (Ro5-3448), also known as chlorodiazepam and 2'-chloro-diazepam, is a . It was first synthesized by and his team at Hoffman-La Roche in 1960.It is not currently approved for use as a medication, but rather sold as a Efficacy and safety have not been tested in humans.
Ergotamine is an and part of the family o; it is structurally and biochemically closely related to It possesses structural similarity to several and has as a
It is used for treatment of acute attacks (sometimes in combination with Medicinal usage of ergot fungus began in the 16th century to induce yet dosage uncertainties discouraged the use. It has been used to prevent (bleeding after childbirth). It was first isolated from the ergot fungus and marketed as Gynergen in 1921
N-Ethylhexedrone (also known as α-ethylaminocaprophenone, N-ethylnorhexedrone, hexen andNEH) is of the classN-Ethylhexedrone was first mentioned in a series of patents by in the 1960s which lead to the development of the better known drug (MDPV). Since the mid-2010s, N-ethylhexedrone has been sold online
Fuambai Sia Ahmadu (born c. 1969 is a Sierra Leonean-American anthropologist. She has worked for and the British lin the Gambia.
Ahmadu obtained her PhD in social anthropology from the and undertook post-doctoral work at the Department of Comparative Human Development,
Fentanyl provides some of the effects typical of other opioids through its agonism of the . Its strong potency in relation to that of morphine is largely due to its highper the Because of this, it can more easily penetrate the
BROMADOLINE is the same effect with u-47700
Alprazolam is mostly used to treat and due to The FDA label advises that the physician should periodically reassess the usefulness of the drug. Alprazolam may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. Alprazolam is also often prescribed with instancesco-morbid sleep deficits.
α-PVP, like other psychostimulants, can cause hyperstimulation, paranoia, and hallucinations. α-PVP has been reported to be the cause, or a significant contributory cause of death in suicides and overdoses caused by combinations of drugs. α-PVP has also been linked to at least one death where it was combined with and caused
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"Methylone" is also a trademarked brand name for an injectable form of methylprednisolone, a corticosteroid hormone used to treat arthritis and severe allergic reactions; hence, methylone may be confused with it. Aside from context, they can be distinguished by the fact that the name will usually be capitalized when referring to the prescription drug.
A proposed alternate name is bk-MDMA, or beta-keto-MDMA. While this nomenclature has not caught on because the name "methylone" became widely used before the conflicting Methylone trademark was noticed, the analogous names for related chemicals bkmdea and bkmbdb have become the established names for those substances.