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From Wikipedia, the free encyclopediaThis article is about the drug substance alpha-PVP, also known as flakka. For the pharmaceutical excipient called PVP, see polyvinylpyrrolidone.alpha-PyrrolidinopentiophenoneClinical dataRoutes of
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-Pyrrolidinopentiophenone (also known as -pyrrolidinovalerophenone, -PVP, O-2387, -keto-prolintane, Prolintanone, or Desmethyl Pyrovalerone) is a synthetic stimulant of the cathinone class developed in the 1960s that has been sold as a designer drug. Colloquially it is sometimes called flakka orgravel. -PVP is chemically related to pyrovalerone and is the ketone analog of prolintane.
Mephedrone, also known as 4-methyl methcathinone (4-MMC) or 4-methyl ephedrone, is a synthetic stimulantdrug of the amphetamine and cathinone classes. Slang names include drone, M-CAT, White Magic and meow meow.It is chemically similar to the cathinone compounds found in the khat plant of eastern Africa, but more closely relates to the mosquito repellent DEET. It comes in the form of tablets or a powder, which users can swallow, snort or inject, producing similar effects to MDMA, amphetamines and cocaine.
In addition to its stimulant effects, mephedrone produces side effects, of which teeth grinding is the most common. The metabolism of mephedrone has been studied in rats and humans and the metabolites can be detected in urine after usage.
Mephedrone was first synthesised in 1929, but did not become widely known until it was rediscovered in 2003 at which point it was legal to produce and possess in many countries. By 2007, mephedrone was reported to be available for sale on the internet, by 2008 law enforcement agencies had become aware of the compound, and by 2010, it had been reported in most of Europe, becoming particularly prevalent in the United Kingdom.
Mephedrone was first made illegal in Israel in 2008, followed by Sweden later that year. In 2010, it was made illegal in many European countries and in December 2010, the EU ruled it illegal. In Australia, New Zealand and the United States, it is considered an analog of other illegal drugs and can be controlled by laws similar to the US Federal Analog Act.
In September 2011, the US temporarily classified mephedrone as a Schedule I drug, effective October 2011. This classification was made permanent in July 2012 with the passage of the Synthetic Drug Abuse Prevention Act (SDAPA).
Methylone (also known as "3,4-methylenedioxy-N-methylcathinone", "MDMC", "k-MDMA" and by the slang term "M1") is an empathogen and stimulant psychoactive drug. It is a member of the substituted amphetamine,substituted cathinone and substituted methylenedioxyphenethylamine classes.
Methylone is the substituted cathinone analog of MDMA and the 3,4-methylenedioxy analog of methcathinone. The only structural difference of methylone with respect to MDMA is the