Opioid Pharmaceutical Intermediates U 48800 research chemical Powders CAS 82657-23-6
1. Samples are provided for test;
2. Good quality products;
3. 100% secure delivery.
Systematic (IUPAC) name: 3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide
U-48800 is an opioid analgesic drug developed by a team at Upjohn in the 1970s that acts as a selective agonist of the µ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor and has around 7.5 x the potency of morphine in animal models.
U-48800 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that U-48800 was the most active.
U-48800 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures.
Although not used medically, the selective kappa ligands are used in research.
Payment ways:, Moneygram, T/T
Delivery:EMS/ EUB/ USPS/ UPS/ TNT/ FEDEX/ DHL etc
Packaging:safe and discreet packaging
Fanchuang Chemicals Biotechnology Co., Limited specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on.
Products: Cannabinoids(5f-adb, bb-22, sdb-005......); Stimulants(a-pvp, M1, Methylone, he-xen, pvp......);
Hot sell products: 4cec 4cdc clpvp etizolam 2fdck and so on
Our products are produced on the basis of best technical team, advanced equipment, high qualified management which meets the requirements of security and environmental protection.
We earned customers' trust and created a good reputation during these years. we are committed to providing excellent quality products and the perfect service to friends all over the world.
We will provide the most comprehensive products and service to you!
We are looking forward to your cooperation.