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Tebipenem Pivoxil (L-084; Orapenem; L084) Tebipenem Condensation Compound Cas 161715-20-4

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Tebipenem Pivoxil (L-084; Orapenem; L084) Tebipenem Condensation Compound Cas 161715-20-4

Large Image :  Tebipenem Pivoxil (L-084; Orapenem; L084) Tebipenem Condensation Compound Cas 161715-20-4

Product Details:

Place of Origin: China
Brand Name: R&M
Certification: ISO 9001, USP, GMP
Model Number: 01

Payment & Shipping Terms:

Minimum Order Quantity: 1g
Price: negotiation
Packaging Details: vaccum packing of aluminum foil bag
Detailed Product Description
Molar Mass: 497.63 G/mol Purity: 99%
Cas: 161715-24-8 Name: Tebipenem
Formula: C15H24N4O6S2

Tebipenem
Clinical data
Trade names Orapenem
Routes of
administration
Oral
Legal status
Legal status · Prescription-only in Japan; investigational elsewhere
Identifiers

IUPAC name[hide]

· (4R,5S,6S)-(Pivaloyloxy)methyl 3-((1-(4,5-dihydrothiazol-2-yl)azetidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

CAS Number · 161715-24-8 [No]
KEGG · D09598
PDB ligand · 1TE (PDBe, RCSB PDB)
Chemical and physical data
Formula C22H31N3O6S2
Molar mass 497.63 g/mol
3D model (JSmol) · Interactive image

SMILES[hide]

· [H][C@]12N(C(C(OCOC(C(C)(C)C)=O)=O)=C(SC3CN(C4=NCCS4)C3)[C@@H]2C)C([C@@]1([C@H](O)C)[H])=O

 

Tebipenem (brand name: Orapenem) is a broad-spectrum orally-administered antibiotic, from the carbapenem subgroup of β-lactam antibiotics. It was developed as a replacement drug to combat bacteria that had acquired antibiotic resistance to commonly used antibiotics. Tebipenem is formulated as the ester tebipenem pivoxil due to the better absorption and improved bioavailability of this form.[3] It has performed well in clinical trials for ear infection and looks likely to be further developed in future. It is only marketed in Japan. Tebipenem is the first carbapenem whoseprodrug form, the pivalyl ester, is orally available. 

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