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Brinzolamide Pharmaceutical Raw Powder For Antiglaucoma , CAS 138890-62-7

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Brinzolamide Pharmaceutical Raw Powder For Antiglaucoma , CAS 138890-62-7

Large Image :  Brinzolamide Pharmaceutical Raw Powder For Antiglaucoma , CAS 138890-62-7

Product Details:

Place of Origin: China
Brand Name: R&M
Certification: ISO 9001, USP, GMP
Model Number: 01

Payment & Shipping Terms:

Minimum Order Quantity: 1g
Price: negotiation
Packaging Details: vaccum packing of aluminum foil bag
Detailed Product Description
Pro. Name: Dorzolamide Purity: 99%
Cas: 130693-82-2 IUPAC Name: (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
Formula: C10H16N2O4S3 Appreance: White Powder

Pharmaceutical Raw Powder Brinzolamide For Antiglaucoma CAS 138890-62-7


 

Quick Detail:

Product Name

 

Brinzolamide

Synonym

 

Birnzolamide;Brinzolamide;2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide,(4R)-;2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (R)-;AL 4862;Brinlolamide;(R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide;(4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide

CAS

 

138890-62-7

MF

 

C12H21N3O5S3

MW

 

383.51

Appearance

 

White Powder

Grade

 

Pharma Grade

Melting Point

 

130.0 to 134.0 °C

Usage

 

It is carbonic anhydrase inhibitors suitable for treating high intraocular pressure or open-angle glaucoma


 

Description


 

Brinzolamide is a carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Carbonic anhydrase is found primarily in erythrocytes(but also in other tissues including the eye). It exists as a number of isoenzymes, the most active of which is carbonic anhydrase II (CA-II).


 

Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion and thus lowers the intraocular pressure in the anterior chamber, presumably by reducing the rate of formation of bicarbonate ions with subsequent reduction in sodium and fluid transport; this alleviates the effects of open-angle glaucoma.


 

Dosage


 

Shake uniformly before using. As a monotherapy or co-therapy, drop one drop into the conjunctival sac 2 times per day; 3 times a day may be better for some patients.


 

When use it as a substitute of another anti-glaucoma drug. Stop using that drug first and start using brinzolamide eye drops in the next day.


 

Treatment with more than one drug should be separated by at least five minutes. It is generally recommended that oppress nasolacrimal duct or gently close your eyes after the medication in order to reduce systemic absorption.

 

Certificate of Analysis

TEST SPECIFICATIONS RESULTS
Appearance White to yellow crystalline powder White crystalline powder
Identification A. Should meet the requirement Conforms
B. Should meet the requirement Conforms
Impurity A ≤0.5% N.D.
Impurity B ≤0.3% 0.075%
Loss on drying ≤0.5% 0.085%
Residue on Ignition ≤0.1% 0.045%
Residual solvent Ethanol≤0.5% 0.026%
Ethyl acetate≤0.5% N.D.
Tetrahydrofuran≤0.072% N.D.
Heavy Metal ≤20ppm Conforms
Assay 98.0%~102.0% (Calculated on the dried basis) 99.66%


 

Advantage


 

1 High quality with competitive price
1) Standard: Enterprise Standard
2) All Purity≥98%
3) We are manufacturer and can provide high quality products with factory price.


 

2 Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.


 

3 We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

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