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|Molecular Formula:||C19H18N4O2||Appearance:||Detailed See Specifications|
|Storage:||Store In Dry, Dark And Ventilated||Transportation:||By Air Or By Ocean Shipping|
|AHFS/Drugs.com||International Drug Names|
|Bioavailability||60 to 65%|
|Chemical and physical data|
|Molar mass||334.37 g/mol|
|3D model (JSmol)||
Pimobendan Basic Information
|Alias||pimobendane, tradenames Vetmedin, Acardi, Heartmedin|
|Appearance||white Crystalline Powder|
|Packing Methods||foil bag or as your mind|
|Delivery time||within 18 hours after payment confirmed|
|Payment||T/T, Western Union,Money Gram , Bitcoin|
|Usage||Pimobendan is a cardiotonic agent.
Pimobendan is an antiviral drug. Pimobendan is used to treat heart disease
Pimobendan is a positive inotrope (increases myocardial contractility). It sensitizes and increases the binding efficiency of cardiac troponin in the myofibril to the calcium ions that are already present in systole. In normal hearts it increases the consumption of oxygen and energy to the same degree as dobutamine but in diseased hearts it may not. Pimobendan also causes peripheral vasodilation by inhibiting the function of phosphodiesterase III. This results in decreased resistance to blood flow through systemic arterioles, which decreases afterload (decreases the failing heart's workload) and reduces the amount of mitral regurgitation.
Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction.
|Appearance||White or slightly yellowish Powder||Slightly yellowish|
|solubility||Practically insoluble in water, freely soluble in dimethylformamide, slightly soluble in acetone and in methanol.||Conforms|
|Identification||Infrared absorption spectrophotometry , Comparison pimobendan CRS||Conforms|
|Related substances(HPLC)||Impurity A:≤0.1%||0.03%|
|Any other impurity:≤0.1%||0.05%|
|Conclusion||The results conforms with Enterprise standards|