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| ProName: | Pimobendan | CasNo: | 74150-27-9 |
|---|---|---|---|
| Molecular Formula: | C19H18N4O2 | Appearance: | Detailed See Specifications |
| Storage: | Store In Dry, Dark And Ventilated | Transportation: | By Air Or By Ocean Shipping |
| High Light: | active pharmaceutical ingredients,bulk drug intermediates |
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Pimobendan Basic Information
| Product Name | Pimobendan |
| Alias | pimobendane, tradenames Vetmedin, Acardi, Heartmedin |
| CAS | 74150-27-9 |
| MF | C19H18N4O2 |
| MW | 334.37 |
| EINECS | 211-390-9 |
| Purity | 99.50% |
| Grade | Pharmaceutical Grade |
| Appearance | white Crystalline Powder |
| Brand Nmae | HKYC |
| Standard | USP |
| Stock | Mass Stock |
| Shelf Life | 2years |
| Packing Methods | foil bag or as your mind |
| Delivery time | within 18 hours after payment confirmed |
| Payment | T/T, ,Money Gram , Bitcoin |
| Usage | Pimobendan is a cardiotonic agent. Pimobendan is an antiviral drug. Pimobendan is used to treat heart disease |
Pimobendan Description
Pimobendan is a positive inotrope (increases myocardial contractility). It sensitizes and increases the binding efficiency of cardiac troponin in the myofibril to the calcium ions that are already present in systole. In normal hearts it increases the consumption of oxygen and energy to the same degree as dobutamine but in diseased hearts it may not. Pimobendan also causes peripheral vasodilation by inhibiting the function of phosphodiesterase III. This results in decreased resistance to blood flow through systemic arterioles, which decreases afterload (decreases the failing heart's workload) and reduces the amount of mitral regurgitation.
Pimobendan Usage
Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction.
Pimobendan Specification
| Item | Specifications | Results |
| Appearance | White or slightly yellowish Powder | Slightly yellowish |
| solubility | Practically insoluble in water, freely soluble in dimethylformamide, slightly soluble in acetone and in methanol. | Conforms |
| Identification | Infrared absorption spectrophotometry , Comparison pimobendan CRS | Conforms |
| Heavy metals | ≤10ppm | 1ppm |
| Water | ≤1.0% | 0. 1% |
| Assay (HPLC) | 98.0%~100.0% | 99.83% |
| Sulphated ash | ≤0.1% | 0.01% |
| Related substances(HPLC) | Impurity A:≤0.1% | 0.03% |
| Impurity B:≤0.1% | 0.07% | |
| Any other impurity:≤0.1% | 0.05% | |
| Total impurity:≤0.2% | 0.17% | |
| Conclusion | The results conforms with Enterprise standards | |
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